I was asymptomatic from Jan 2013 until September 2022 with Bronchiectasis and Mycobacterium simiae. I chose not to have treatment. I was being seen at Brook Army Medical Center In San Antonio(Fort Sam Houston) pulmonary clinic. I was doing great with my PFTs and had zero issues. Then I coughed up blood in September 2022 and the Abscessus popped up. If I had been seen at BAMC during COVID, I believe it MAY have been possibly caught sooner. My VA pulmonologist, states it was GOOD not to have been treated(w/meds) when I had few symptoms. Your fatigue and SOB sounds like it may be time for you. Are you losing weight? I have lost eight to ten pounds.