ADT with EBRT and Brachytherapy

Fortunately, I live in Ontario, you know, your friendly neighbour above the crack house. I am not sure that these interventions are available here, but I’ll inquire.

They are more likely to agree to genetic tests if you have cancer in your family. If you don’t know exactly what kind someone had you might find out before requesting testing from your doctor.

I would if I knew who my genetic donor was.

You ll always be a friendly neighbor. Try some white button mushroom powder in your coffee/ tea- studies are still in progress on this subject.

Here is a link that may provide some guidance on obtaining germline testing in Ontario given your cribform patholigy: https://pmc.ncbi.nlm.nih.gov/articles/PMC10581723/.

I want to add how much I enjoy the phrasing of your posts, notwithstanding the seriousness of the content.
Bill

He does have a dry wit, doesn’t he? I always look forward to his posts even though, as you say, the subject matter is less than funny.

Thank you. Appreciate the link and I'll ask about this after my today's visit to the zap machine.

An additional link to Cancer Care Ontario's page of guidelines. At the center of the page is a link to their specific guidelines by cancer type.
"Hereditary Prostate Cancer
Prostate cancer is a common malignancy that is frequently associated with hereditary cancer
syndromes, particularly when individuals present with advanced and/or metastatic disease. Evidence of
high risk, invasive disease may be found in pathology reports, operative reports, urology notes and/or
oncology notes. A history of systemic chemotherapy, distant metastasis and/or death due to disease
can be considered sufficient evidence to confirm metastatic prostate cancer in a patient or family
member. Hereditary cancer testing can be considered for individuals with a:
1. Personal history of metastatic prostate cancer.
2. Documented personal history of high risk, locally advanced, prostate cancer.
• High risk prostate cancer can be confirmed with evidence of one or more of the following
features:
• T3 (or higher) staging11, Grade Group 4 or 5 (Gleason Score 8 to 10)
12, lymph node
involvement, PSA ≥20.
3. Personal history of prostate cancer with ≥1 close relatives with prostate cancer.
• One relative must have evidence of high risk or metastatic disease.
4. Personal history of prostate cancer with ≥2 close relatives13 with prostate, pancreas, ovarian and/or
breast cancer regardless of age or stage.
Note: There is currently conflicting evidence for prostate tumours with intraductal/ductal pathology and
this feature is not considered to be independently sufficient to confirm eligibility for genetic testing at
this time. The evidence will be reviewed periodically and this criteria will be amended if needed."
https://www.cancercareontario.ca/en/guidelines-advice/types-of-cancer/70161

I don't know if you have had a post-treatment PSA, but I can warn you that my 9.0 PSA spiked to 11.96 after SBRT.
It has since declined, but seeing a post treatment jump is not unheard of. Radiation can be quite a rollercoaster ride.

Most often I have net zero cognitive content.