I have tried the nicotene patches. The first day I used a whole one (lowest dose) and felt super energized, so I started cutting them in half. Was not so sure it was doing anything. I wore them for two weeks while traveling but still experienced post-malaise from the trip. There was only enough for 2 weeks so I would like to learn more about what protocol to use. I will look up the link suggested in an earlier comment. I am planning to meet with my primary doctor this week to discuss the latest research.