HRT Safety
I wanted to share this Medscape article I received today about new study on HRT. I am considering HRT for my osteoporosis at age 67 and am so encouraged by this article: https://www.medscape.com/s/viewarticle/hormone-therapy-after-65-good-option-most-women-2024a10007b2?ecd=mkm_ret_240608_mscpmrk_obgyn_menopause_etid6577682&uac=36
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I have never had symptoms from my osteoporosis. In 2019, at age 62, I began high dose prednisone for my autoimmune condition. I asked my PCP for a dexa as I had read this was recommended when starting prednisone. That is how I discovered my osteoporosis with a spine t score of -2.8 5 and 1/2 years ago.
I see.
Hi Debbie…my cardiologist was very progressive and highly educated in the use of BHRT. When he initially ran my bloods and all my cardiac screenings, he said I needed hormone replacement therapy. He was very confident that I would benefit from adding that to what I was already doing (D3, calcium, magnesium, K2 (for my bones). I am on a 0.25 mg Estradiol patch, 125mg capsule of progesterone and 0.5 mg of testosterone creme daily. I’m also pretty active (pickleball, weights, cardio). Of course my rheumatologist was livid that I was taking a break from the traditional meds, after Tymlos and said the hormones would do no good…and she may be right, (I hope not), but I had to give it a try. I went off Tymlos in July of last year with a 15% gain in my spine and 5.5% gain in my hip after 2 years. If I could have continued the Tymlos therapy I would have…very few side effects. My integrative doc took over my cardiologist’s hormone patients after he unexpectedly passed a few months ago but she is also educated in hormone therapy and continues to prescribe what I need.
This journey comes with so much conflicting information but I try to stay educated and pray the choices I’m making will benefit me physically and mentally. 🌹Rose
Hi Rose, thank you for sharing all your information. It is a treasure trove of knowledge for me reading about your experience with medical professionals and treatments. Have you had a CTX to check your rate of bone turnover on the BHRT? I think it's not unreasonable that the BHRT could maintain your gains, but time will tell as you say. I'll be anxious to know how things go for you. I wish you all the best.
Has anyone tried bio-identical transdermal estrogen/progesterone therapy and started it at over 70 years old? (Or even started the patch after age 70) I feel like the lack of hormones are wreaking havoc on my body-sleep, mood, energy, vaginal dryness and atrophy etc but I have had limited trials of low dose bio-identical in the past 5 years and have had side effects such as bloating, water retention, PMS-like symptoms and cramping. I’m 71 and wondering after all this time not having estrogen and progesterone in my body (blood tests showed almost none) that my body no longer knows what to do about these hormones! I read the best time to start HRT is right after menopause. I really never had the need to consider HRT until the past 5 years. Thankfully, my daily walks, having been a strong and physically active woman all my life and supplements have kept me from osteoporosis but I am in osteopenia with 2 vertebrae now showing osteoporosis due to arthritis and I cannot even consider osteoporosis drugs because I am extremely sensitive to drug side effects.
Hello,
How long have you been taking HRT? Do you take DHEA as well? Any other supplements. 60 yr old postmeno with osteoporosis trying to treat naturally
I have been taking BHRT for 10 months. I am 68 and 14 years post menopause. Here is the very long list of supplements I take: calcium, vitamin D, collagen, magnesium, boron, curcumin, resveratrol, quercetin, milk thistle, N acetyl cystein, alpha lipoic acid, acetyl l-carnitine, K2 MK4, K2 MK7, omega-3s, berberine. Some of these I take also to manage my cholesterol, triglycerides, pre-diabetes and vasculitis autoimmune condition, but Keith McCormack also recommends them for osteoporosis. I was taking these before I saw the menopause society naturopath, but she said to continue on them. The berberine made a definite difference on cholesterol, triglyceride, and A1C lab tests. The Omega 3s also lowered my triglycerides and NAC/milk thistle lowered my liver enzymes. No I don't take DHEA. Are you taking this?
Started HRT at 74 yrs. I had a partial hysterectomy when I was 44. I have osteopenia, coronary heart disease, and managed vulva and vaginal atrophy.
This is my regime:
Transdermal Estradiol .05, patch, 2x a week (Cardiologist approved)
Estradiol Vaginal Cream 0.01% 2-3 times a week
Testosterone 4mg, DHEA 25 mg cream, used daily on vulva and clitoris and systemically on thighs.
2x a week I use an over-the-counter product, vaginal hyaluronic acid RepaGyn.
I take 2.5 mg of tadalafil (Cialis) daily to maintain the overall health of my heart, brain, bones, and blood flow to the vulva and clitoris.
@debbie1956 , I look forward to hearing your updates, bone markers or dexa! We used same dosage and form - E2 0.025mg/day patches and oral 100mg micronized progesterone at aroud similar time. My CTX at 6mo HRT was 163, which suggested "against active bone breakdown" per my endo, my dxa also indicated further bmd increase by a significant margin. It will be interesting to compare our results even though I transitioned from Forteo to HRT while you started from a drug-naive state. Fingers crossed.
@kisu , thanks for sharing! What did your dexa results say about your HRT regimen? What about bone markers (CTX and/or P1NP) if you could share? I'm very curious what effect testosterone could add to the usual estrogen + progestin. Your bone markers or dexa results may give us some information.