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Is PSA rise inevitable after hormone therapy?

Prostate Cancer | Last Active: 3 days ago | Replies (45)

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@northoftheborder

Hormone therapy and ARSI are still working for me. I don't know for sure what we'll do if/when they "fail" (which is what Dr Kwon is discussing, according to @nparadisum).

I'd think chemo and/or Pluvicto might end up being good options, or maybe trying a different -lutamide. Or maybe I'll never get there, or at least won't until there are new treatment alternatives.

Also, if there are only a couple of hotspots on a PSMA PET scan, we might be able to radiate them directly and reset the clock, so to speak.

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Replies to "Hormone therapy and ARSI are still working for me. I don't know for sure what we'll..."

A quick Google and the answer is Docetaxel, which is already extensively used in triplet therapy or alone after ADT failure.
Many on the forum have used this drug and reported success; also, the fearsome side effects of “chemo” seemed to be felt to a lesser degree by most patients.
Having not gotten to that stage myself ( hopefully NEVER🤞) I was not familiar with the taxane family of drugs, sorry…