ApoB is important and also APOE
(Apolipoprotein E) affects lipid levels by modifying lipid metabolism and the risk of neurodegenerative diseases. The APOE4 allele is associated with triglyceride and cholesterol accumulation in glia, as well as modulation of immune reactivity. APOE is a lipid-binding protein that transports triglycerides and cholesterol in multiple tissues.
The APOE gene gives your cells instructions to make apolipoprotein E. This protein merges with fats (lipids) to form lipoprotein molecules. Lipoproteins carry cholesterol and other fats through your bloodstream.

There are three types (alleles) of the APOE gene:

APOE-ε2 (APOE2).
APOE-ε3 (APOE3).
APOE-ε4 (APOE4).
All humans inherit one copy of the APOE gene from each of their biological parents.

The combination of alleles may increase your risk of certain health conditions by affecting how your body is able to move cholesterol and other fats through your bloodstream.