HRT Safety

Posted by debbie1956 @debbie1956, Jun 8, 2024

I wanted to share this Medscape article I received today about new study on HRT. I am considering HRT for my osteoporosis at age 67 and am so encouraged by this article: https://www.medscape.com/s/viewarticle/hormone-therapy-after-65-good-option-most-women-2024a10007b2?ecd=mkm_ret_240608_mscpmrk_obgyn_menopause_etid6577682&uac=36

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@kshea2

This is fantastic information, thank you! Your results look very encouraging. I was not aware of the NA Society, so will leverage that source to help find a provider.

I'm just turning 62 and had a dexa in December, 2024 which showed Spine -2.9 (Osteoporosis) /Total Hip -1.8/Femoral Neck -1.8 T-Scores (osteopenia) . Unfortunately one week later I fainted, fell and experienced a compression fracture in T12. January, 2025 I had a Echolight scan which showed Spine -2.2 (Osteopenia)/Femur -2.5/Right-2.9 (Osteoporosis). Fragility scores are in the green zone. I know you can't really compare these types of scans 1:1, but it's a bit confusing.

I've taken Vitamin D for years and have now added K2 and Magneium. I'm working hard to get more calcium through diet. I'm very nervous about the drug therapies and believe HRT could also help with sleep and couple other post menopause issues I experience.

Hoping I can find a provider in the Minneapolis area that is open to this approach. I'm looking forward to hearing your updates! Thanks again!

Jump to this post

I forgot to mention it is notable that your Echolight showed your fragility score in the green zone and yet you still fractured. This is another stark reminder these results can sometimes give us a false sense of security, and make me reflect on my own Echolight fragility score. I wish you all the best and a full recovery from your fracture.

REPLY

Where do you all get those scores for bone health?

REPLY

I have had 3 DEXA bone scans and 2 REMS Echolight scans over a 5 year period. DEXAS are covered by our medical plan, but I have to pay for private Echolight scans. My blood lab tests are mostly ordered by my PCP covered by our medical plan. If my PCP won't order them, the naturopath physician does this in which case I have to pay the lab but have some limited private benefit coverage. My PCP wouldn't order the CTX or vitamin D. The CTX is vital to know my rate of bone turnover and later to see if my interventions -- HRT, supplements, diet, exercise etc. -- are working to lower the bone turnover rate. My understanding is that the CTX can come down before the bone density score improves on the DEXA, which shows the interventions are working and success in stopping further bone loss progression if bone turnover is low enough.

REPLY
@nme1985

I am in the exact same position, avoiding medicines at all cost. My endocrinologist is not happy about that as she does not believe in any alternative medicine. I told her if my bones start to really decrease then I will consider meds. I have been holding at worst -2.2 after hormone replacement treatment, My forearm is -4 which it has been for the past 20 years. I don’t even know if most doctors measure the forearm, My doctor is going off of that one score. I pray every day that I remain steadfast in my numbers and they continue to at least stay the same if not improve. As I have mentioned before on this site, my doctor wanted me to go on Prolia 15 years ago!!!! I can’t imagine where I would be today if I did that. My numbers are better now than they were then as far as the DEXA, but I did supplements and exercise, etc., and the HRT.

Jump to this post

@nme1985 Thanks for sharing your experience. Your numbers look great to me. Your story is encouraging around the benefits of HRT. Yes, I think you made a good decision in not taking Prolia. It sounds like a scary high risk medication and who would want to be on it for life at your younger age! It sure wouldn't be my drug of choice if I ever need to take an OP medication!

REPLY
@debbie1956

@nme1985 Thanks for sharing your experience. Your numbers look great to me. Your story is encouraging around the benefits of HRT. Yes, I think you made a good decision in not taking Prolia. It sounds like a scary high risk medication and who would want to be on it for life at your younger age! It sure wouldn't be my drug of choice if I ever need to take an OP medication!

Jump to this post

Thank you for replying. I am so anxious this morning thinking of this osteo and whether I am making the correct choices. I just have to do my best for now and trust my instincts. Thank you so much Debbie! 💗

REPLY
@debbie1956

I have had 3 DEXA bone scans and 2 REMS Echolight scans over a 5 year period. DEXAS are covered by our medical plan, but I have to pay for private Echolight scans. My blood lab tests are mostly ordered by my PCP covered by our medical plan. If my PCP won't order them, the naturopath physician does this in which case I have to pay the lab but have some limited private benefit coverage. My PCP wouldn't order the CTX or vitamin D. The CTX is vital to know my rate of bone turnover and later to see if my interventions -- HRT, supplements, diet, exercise etc. -- are working to lower the bone turnover rate. My understanding is that the CTX can come down before the bone density score improves on the DEXA, which shows the interventions are working and success in stopping further bone loss progression if bone turnover is low enough.

Jump to this post

Is this a screening or done due to symptoms?

REPLY

Hope all goes well for you. I too am not taking any of the hard drugs because I react to everything. I started about 12 months ago doing supplements and my last dexa showed a 12% improvement. I believe my osteoporosis began when my thyroid was removed for cancer. Getting the thyroid replacement meds right is a BIG deal - I think. My endo and I parted ways because he did not want to hear me and basically said he couldn't help me any more if I'm not willing to take the harsh medicines. I'm on track for a new Endo in early April. Anxious to see what blood work shows. My thyroid meds have been increased twice since that time by my regular doctor and I added back to the supplements K2 because D3 doesn't work without it. Feeling much better and pain level is down. Planning on joining gym next week to start strengthening muscles and will continue walking 3 miles 3-4 times a week. Praying for you ladies to find your answers and help to this awful diagnosis

REPLY
@debbie1956

I forgot to mention I am using the Estradiol patch with micronized Progesterone. I am experiencing no side effects except improved sleep and mild calming effect. The naturopath recommended a Coronary Artery Scan. With a score of zero she said my risk on HRT was minimal and arteries would be quite receptive to Estrogen still. She checked my cholesterol, A1c, triglycerides etc., ordered another CTX, vitamin D and recommended a Lipo A test.

Jump to this post

@debbie1956 hello, can I ask what the dosage is on ur estradiol patch? Your post is very encouraging. I was on Tymlos for 2 years and had great gains in my spine but my rheumatologist wanted me to begin Evenity to continue building bone after that. I was hesitant but my cardiologist suggested BHRT as I was lacking in hormones and said it could stabilize my bones as well. I have an appt with my integrative doc in April and will have bloods drawn to see if the hormones are working. I had a clear calcium scan done a couple years ago so my cardiologist felt confident BHRT would be fine. I’m on 0.025 Estradiol patch, I’m also taking progesterone by mouth and testosterone creme. The only thing I notice is a stubborn bit of weight gain especially in my stomach. I’d like to get a Rems echolight but need to find one in my area. Praying the hormone replacement is working. I’m 73 and had a total hysterectomy when I was 38 so therein the severe osteoporosis. Thanks for sharing. Rose

REPLY
@debbie1956

@kshea2 I'm so sorry to hear about your fall and fracture. I hope you are not suffering a lot of pain. This is a stark reminder of how fragile and vulnerable we are often without knowing. Your REMS Echolight scores are interesting. The difference in your spine T score compared to DEXA is similar to my initial Echolite spine score compared to DEXA. Mine was .5 lower than the dexa and yours .6. My femur neck T score however was the same as the dexa score at -2.6. My second Echolite 10-months later showed my femur neck at -2.3. When I was initially diagnosed with osteoporosis in 2019 with spine T score -2.8, I took calcium and vitamin D for the next 4 years but still rapidly lost bone to a level of -3.5. However I was taking high dose prednisone during 2019/20 for a year for an autoimmune condition. I began many other supplements and diet changes, including increased calcium from food sources, increased protein, K2 Collagen...suggested by Keith McCormick in December of 2023. I find the nutritional and supplement counseling another benefit of the N.A. Menopause Society naturopath. I provided her records of all my DEXAS, Echolight, CBC lab tests, including urine calcium, CTX, vitamin D etc. My blood tests were mostly fine, including vitamin D, calcium and urine calcium. My CTX was at 670 which the naturopath and osteoporosis doctors surprisingly said was okay (Lab test shows 100 to 1000 is acceptable) However Keith McCormick says this number is too high and should ideally be below 400. So it will be interesting to see the result of my follow-up CTX next week. I have heard that HRT can reduce the rate of bone turnover (confirmed also on chat GPT). I consulted with an internal medicine doctor specializing in osteoporosis in May of 2024. She recommended Evenity. I said I would like to hold off to see if I could stop the progression of bone loss first and consulted with the naturopath in July of 2024.

Jump to this post

Thank you, I am healing well and the pain is now minimal as long as I am careful with my posture. I tend to slouch and that is the worst thing for spine health and the healing process.
The specialist I saw after the the fall also recommended Evenity. He would not even discuss HRT and said he would have to send me to Endocrinology. I have a feeling that would be one more expensive appointment only to be told no. I a couple leads on providers for HRT so will keep everyone updated on progress.

REPLY
@dooshie

@debbie1956 hello, can I ask what the dosage is on ur estradiol patch? Your post is very encouraging. I was on Tymlos for 2 years and had great gains in my spine but my rheumatologist wanted me to begin Evenity to continue building bone after that. I was hesitant but my cardiologist suggested BHRT as I was lacking in hormones and said it could stabilize my bones as well. I have an appt with my integrative doc in April and will have bloods drawn to see if the hormones are working. I had a clear calcium scan done a couple years ago so my cardiologist felt confident BHRT would be fine. I’m on 0.025 Estradiol patch, I’m also taking progesterone by mouth and testosterone creme. The only thing I notice is a stubborn bit of weight gain especially in my stomach. I’d like to get a Rems echolight but need to find one in my area. Praying the hormone replacement is working. I’m 73 and had a total hysterectomy when I was 38 so therein the severe osteoporosis. Thanks for sharing. Rose

Jump to this post

@dooshie Thank you for sharing your information. I also have a .25 Estradiol patch and 100 mg of micronized progesterone. It is encouraging to hear that your cardiologist suggested BHRT. I'm not aware ofhear medical doctors recommending this where I live in Canada. It's also interesting that your hormone levels were tested. My naturopath said she could test me if I wished but that this wasn't necessary. She said she would not be increasing my level of estrogen which was somewhat surprising. Did your functional medicine doctor recommend testosterone cream? My naturopath also dismissed testosterone when I asked about it. I am aware of others who have a higher level Estradiol patch but .25 isn't unusual from other posts I've seen. Did you have good results from the Tymlos?

REPLY
Please sign in or register to post a reply.