← Return to Help-what treatment plan has anyone selected for Perineural invasion?

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@heavyphil

The perineural invasion is not your worry - it’s fairly common. It’s the high grade epithelium/ high Decipher Score risk that’s a concern.
Your age and overall health are VERY important in making your decision.
At 74, with some co-morbidities like brittle diabetes, hard to control HBP or advanced heart disease, radiation would be the better option.
However, if you are a fit and trim 74 with no other major health issues (uncontrolled by meds), surgery is a good choice because your type of cancer could return - no matter the initial treatment - and you could then do radiation/ADT to attempt a cure.
I just advised a friend NOT to have surgery at age 75 since his cancer is low grade, low Decipher and he has a lot of medical issues. Best,
Phil

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Replies to "The perineural invasion is not your worry - it’s fairly common. It’s the high grade epithelium/..."

Why is HGPIN a big concern? It is still pre-cancerous, right?

@thecure74, are tou saying that 12 cores in the biopsy were positive? Or only those three you mention with PNI and HGPIN?