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Rising PSA years after radical prostatectomy

Prostate Cancer | Last Active: Mar 22 9:18am | Replies (231)

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@fmcallister1954

I had my prostate removed in July 2019; 5.8 years ago. My PSA has been rising Slowly since at the lowest it was 0.008 in Dec of 2020. since then, it has been rising. I am currently @ 0.074 last PSA test on 14 Feb 25. I was told a slow PSA increase is consistent with a small cancer somewhere in the prostate bed, rather than distant spread. I do not know how true that is, still under 0.1 though, I am hoping the latter of that statement, the consistent part with only in the Prostate bed is correct. Dr says at this point will not show any thing on a PSMA scan. Maybe after it gets to >0.1. IDK

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Replies to "I had my prostate removed in July 2019; 5.8 years ago. My PSA has been rising..."

You’ve got a ways to go before you hit the magic 0.20. My PSA took exactly 5 yrs to go from .02 to .18.
If you do get salvage radiation down the road make absolutely SURE that they radiate the pelvic lymph nodes as well- not just the prostate bed.
Failure occurs when those nodes are not treated. Best,
Phil

The future is always uncertain with PCa.
However, a friend is completing 7 wks of Salvage Radiation Treatment w/o ADT this week at a MD Anderson facility in NJ.
His PSA rose slowly over the last 5 yrs since his RP.
He is doing well, his radiation treatment has been uneventful and he is looking forward to ringing the bell next Friday.
I sincerely hope that is not your course; but know that Salvage Treatment generally is not horrible.
Especially if you can avoid ADT. See SPPORT trial results for breadth of radiation.
I had a short course of ADT as part of my Salvage Treatment and it seems that some men with recurrence are having radiation only.
Either way, I have hope and confidence that you will do well if additional treatment is needed.
Best wishes.