Buyer beware goes the saying. Some people tolerate topical creams or liquids well and might help some. I find this type of product to be an irritant and although not the same brand or name only gave me a more intense burning sensation. Snake oils have always been peddled and will continue to be as long as illnesses attack us and we are desperate to find a cure. There is a presentation by the PN foundation on April 9 that hopefully will provide us more info on what is being pursued to help, I hope, on this matter.