The doctors sequence of giving you Degarelix first and then moving onto the pill is a little strange. What puzzles me is that if he’s going to the pill (Orgovyx) It doesn’t have the flare problem so he could start off with that right away. So many people in here have been getting those Degarelix Injections for a very long time, This is the first time I’ve heard of it only being done once. If he didn’t give you that first, he would have to give you biclutamide Pills for two weeks before Lupron.

As for Gleason scores, The highest number is the only one that counts as far as treatment goes. If his highest combo is 4+5, then he’s a Gleason nine, If it’s 2 fives then he’s a Gleason 10. Having a lower score on some cores isn’t relevant.

As for future radiation. The consensus among doctors these days is that the prostate should be removed for people that have had initial spread to other parts of the body. They want to eliminate the prostate as a cause of future cancer spread. When I say removed, I mean either by radiation or surgery, but it’s usually makes more sense to do radiation when it’s already spread.

While his PSA is high ADT, plus Zytiga, Plus chemo is probably going to bring him down to an undetectable PSA. There’s no telling how long this will last, But no doctor can give you a definitive date. Development of new drugs has been pretty rapid, So by the time these drugs stop working for him, there may be new things out to extend his life. The rest of us out here are hoping for exactly that happening.