Has anyone used the Ibandronate injection to hold in gains?

drsuefowler, I haven't used ibandronate, but it seems like good choice. It isn't as strong as Reclast and your dose will be lower. If you did have a reaction the duration would be shorter. You might try to have it administered as a 30 minute infusion.

Thanks @gently

I'm in the same boat and wondered the same thing. I've just finished Tymlos. Or rather, was taken off of it due to high calcium levels, so now they want to out me on Reclast, but I suggested Boniva quarterly infusions. He says it won't work as well. I need to lock in my gains as well (12.5%) and have only two options now, Reclast or Boniva infusions.

I have explored this option too as i have asymptomatic gerd. Here is a publication on iv ibondronate phase 3 clinical study:
https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.21918
Please share what you and your endos decide and approaches regarding monitoring therapy. Thanks!

Thanks Mayblin. This is a very helpful article. I think I am a ways off
from trying this, unless my Forteo hasn't done anything more to help my
bones according to my next REMS test. I am also still trying to find a Dr
who will prescribe bioidentical estrogen.

@georginas,

Did you have high calcium in your blood? I had very high calcium in my
urine, but my Drs don't seem to care. I worry about kidney stones all the
time. My endo asks me not to take calcium before my blood work and then the
results are normal. I try to eat calcium rich foods as recommended by my
endo, and still take a small supplement.

Keith McCormick, author of Great Bones, used oral Fosamax to hold in his
gains from Forteo. According to the study @mayblin just posted, the
intravenous Boniva is stronger than oral Boniva. I don't know if Boniva is
weaker than Fosamax. Bone markers and periodic REMS tests should be done to
see if it is working. According to the study, some people felt sick the
first time from the intravenous Boniva, but not as severely as with Reclast.

The other option would be to try to take a partial dose of Reclast
like @windyshores did. It all depends on what we can convince our Drs to do
for us. It's nice that the intravenous Boniva is already a small dose every
3 months.

Thanks for posting.

Hello drsuefowler,
Yes, the calcium levels at 10.8 we're going on a blood draw, actually twice, once in January and again in March. I'm January I was going to an alleged bone specialist at the CORE Institute in Arizona. She never followed up with me on my blood work results. I was disappointed and changed doctors, and now I go to an endocrinologist. They took another blood draw and my calcium levels were still at 10.8. I've never had high calcium in my blood, so the Endo told me to stop taking Tymlos. I was on it for just short of 11 months. I'm going in for blood work again on the 27th, and it will be two weeks off Tymlos and calcium supplements, so we will see if there is improvement. I will talk to my provider about ordering a lower dose of Reclast... I hope they will agree to that. When being infused with a lower dose, does this mean that another infusion will be administered sooner than 12 months?

Sorry about the text mistakes. This phone has a mind of its own.

@georginas,
Yes, @windyshores was supposed to have the lower dose Reclast every 3 months. Please let us know what you end up doing and your response.

She had 2 low dose infusions and was able to delay more as her CTX levels were still low when it was time for the next one. I have no idea about how long she was able to hold off.