Hello @besmith57 - in answer to your question, yes - I do take 60mg Duloxatine in the morning plus, 60mg Duloxetine in the evening (so 120mg in total throughout the day). Definitely take the medication with food - even if it’s only a couple of cookies, as that will settle the nausea feeling. The Bupronorphine is an opioid, and my GP had to be given clearance by the pain clinic to prescribe it for me…and the pharmacy needs ID from whoever collects it on my behalf. Thank you for your very kind words - they are greatly appreciated 🤭😊