What imaging studies you had and what contrast agent was used?

Posted by surftohealth88 @surftohealth88, Mar 16 3:11pm

Please help - what imaging technique was used to check for cancer location and possible spread and what agent was used ( Galium ?) ?
Thanks so much in advance !

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gently | @gently | Mar 16 4:23pm

Pylarify is the latest agent.
https://www.pylarify.com/patient-management/impact Called PSMA/PET.
https://pubmed.ncbi.nlm.nih.gov/26013479/

jeff Marchi | @jeffmarc | Mar 16 7:01pm

Both gallium-68 and polarify are used in a Pluvicto scan. Results are similar.

surftohealth88 | @surftohealth88 | Mar 16 7:54pm

Did you guys have PSMA/ MRI and PSMA PET , or just PSMA PET ?

dailyeffort | @dailyeffort | Mar 16 8:04pm

In reply to @surftohealth88 "Did you guys have PSMA/ MRI and PSMA PET , or just PSMA PET ?" + (show)

I just looked at the Mayo, UCSF ans Fred Hutch websites for PSMA Pet scan. They all state the Gallium GA 68 PSMA-11 is used. It is also what I had in the 2022 PSMA clinical trial I was in.

jeff Marchi | @jeffmarc | Mar 16 8:28pm

In reply to @dailyeffort "I just looked at the Mayo, UCSF ans Fred Hutch websites for PSMA Pet scan. They..." + (show)

I know many people that have had Pylarify. It’s discussed occasionally at the weekly Ancan.org meetings.

dailyeffort | @dailyeffort | Mar 16 11:21pm

In reply to @surftohealth88 "Did you guys have PSMA/ MRI and PSMA PET , or just PSMA PET ?" + (show)

I had an MRI and a PSMA PET scan with Gallium in 2021.

UCSF does have anclinical trial ongoing clinical trial with Pylarify.
PYLARIFY® PET/CT or PET/MRI in Men with Favorable Intermediate Risk (FIR) Prostate Cancer. Here is the link: https://clinicaltrials.ucsf.edu/trial/NCT06074510

dailyeffort | @dailyeffort | Mar 17 12:17am

In reply to @dailyeffort "I had an MRI and a PSMA PET scan with Gallium in 2021. UCSF does have..." + (show)

I believe it was originally approved in 2021 for men with suspected metastasis. https://www.fda.gov/drugs/news-events-human-drugs/fda-approves-second-psma-targeted-pet-imaging-drug-men-prostate-cancer#:~:text=FDA%20approved%20the%20first%20PSMA,cancer%20imaging%20indications%20as%20Pylarify.
The current trial at UCSF is a stage 4 open label study to gather data for a broader FDA approval. The safety and efficacy are known and it is an open label trial so you know that Plarify will be used. There should be no cost to you or insurance, but ask so you'll know, if your husband meets the trials criteria. They might also be able to get him in more quickly. Lastly, if it is of interest, it's great to participate in clinical trials to help move the science we all rely on forward.

surftohealth88 | @surftohealth88 | Mar 17 1:43am

Aawee, guys you are amazing < 3. Great friends and so knowledgeable about everything and always with great new ideas and suggestions. 🙂
Tomorrow I will spend day reading all links and doing research about it all. My husband will try to per sway urologist to add PSMA MRI to PSMA PET - keeping fingers crossed. *sigh
Once more, thanks so much for helping and giving me links and all. < 3