← Return to Olaparib for OC stage IV used for 7 years - stop or keep taking? Risk

Discussion
Comment receiving replies
Profile picture for marileenewman @marileenewman

I was diagnosed with BRCA +2 OC in January 2022 stage 3C.
my recent appointment with my oncologist was fine.
CA 125 stable. She does not think I should go back on an PARP inhibitor however, I think I should especially after reading Zanetta 78. I was on just one 100 pill twice a day so a total of 200mg. I worked in pharmaceuticals for years and I think most drug dosages are high because they wanted to get through the FDA for efficacy. There are a lot of drugs we could be on and the dosage could be cut in half. At any rate, I can’t go back on a PARP inhibitor now until my iron is back up and I recover from mypreventativemastectomy, but I won’t be at 12 months without PARP until December 2025. and I too have read that it comes back 12 months after no PARP inhibitor. I would like to see some articles specifically geared towards long-term maintenance doses of PARP inhibitors, but I don’t know that such studies have been done.
in a quandary as well and terrified of getting cancer again.

Jump to this post


Replies to "I was diagnosed with BRCA +2 OC in January 2022 stage 3C. my recent appointment with..."

@marileenewman Hi. I’m on Lynparza daily 150 mg 2x daily. HGSoc stage 111A. Stable cancer antigen for 11 months I experience fatigue and naseau. I really with they had more study’s regarding doseage. I also notice they don’t consider weight, age, or gender in the dosage. I feel overdosed. I’m thinking to take a break every 3 months to recoup, but maybe better to just lower the dose again. Thank you for your comment it was helpful to hear