Something about the brain returning to homeostasis. My NP doesnt believe that but I just don't want to do that, effexor never really even helped that much for me. I hope you're feeling better @secretwhitepop

@sandij
Can you expand more on what you were told about it being dangerous? It's a tricky process weaning someone off one drug and onto another--you would definitely want an experienced and knowledgeable doctor.

@secretwhitepop
GrandmaR mentioned that Effexor didn't work for her as well when reinstated some months/years (?) as it did the first time she was on it.

By the time I realized that I was experiencing Effexor withdrawal effects, I had been off for over 6 weeks. I didn't reinstate Effexor because I read that doing so that far out was unlikely to quickly mitigate my very distressing withdrawal symptoms (1-2 weeks for sleep, energy or appetite to improve and 6-8 weeks for depressed mood and lack of interest in activities to fully improve) and I hoped those 1-8 weeks were better served moving further away from my Effexor use (I no longer needed it for hot flashes).

Could your doctor prescribe a short course of a faster-acting medication (Valium, clonazepam, or Xanax for example) for the anxiety to take along with the Zoloft until the Zoloft fully kicks in?