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Understanding PSA spike and what questions to ask

Prostate Cancer | Last Active: Mar 16 1:17pm | Replies (14)
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@rcroane56

Thank you for the replies. I'm still wondering where the free PSA fits into this and the free/total ratio? Other reading I've done suggests that the spike in the total PSA, accompanied by a total/free ratio of .27, is most likely due to something other than cancer. In my case, I'm hoping it's just my BPH acting up. A couple things I didn't mention in my original post....my father had prostate cancer and I had a biopsy many years ago that was negative.

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Replies to "Thank you for the replies. I'm still wondering where the free PSA fits into this and..."
survivor5280 | @survivor5280 | Mar 13 5:03pm

Your familial history certainly puts you at a higher risk, but again it's not a sure thing. Also the ratio is just statistics, and are only markers for whether or not you need to explore further.

Here's a good writeup on how those numbers work, but try not to self diagnose or let a forum full of non medical professionals guide your decision, we can only share our own experiences and knowledge gained from going through this crap situation.
https://healthmatters.io/understand-blood-test-results/psa-free

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heavyphil | @heavyphil | Mar 14 7:51am

There is a PSE test which looks for biomarkers for cancer. It is touted as being 94% accurate.
You could do this before you move onto the next steps in diagnosis which are more invasive.

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