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PMR to RA?

Polymyalgia Rheumatica (PMR) | Last Active: Mar 18 8:38pm | Replies (22)

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@prestol

I have just been told that I was very likely misdiagnosed 14 months ago by my original rheumatologist. I am seeing a new one who thinks I have late-onset rheumatoid arthritis, which is somewhat different than the early onset type. It has a sudden onset, like PMR, and affects larger joints, such as shoulders and knees, also like PMR. I was sero-negative for RA originally, but now a much more sensitive set of blood markers has become available. It is called “anti-CAR-P” and one of my values (anti CAR-Pab) is high, indicating early stage RA. Also, I had an ultrasound of my shoulders, which revealed areas of bone erosion, which is not usually found in PMR but is indicative of RA. All this info was provided by my pcp, but I see my regular rheumatologist on Monday.

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Replies to "I have just been told that I was very likely misdiagnosed 14 months ago by my..."

Many autoimmune disorders "overlap" with PMR. As unfair as it sounds, people can have more than one autoimmune condition. I have PMR in addition to several other conditions.

RA and late onset RA (LORA) are just one type of inflammatory arthritis. There is a whole family of another type of inflammatory arthritis called the spondyloarthritis family.
https://www.arthritis.org/diseases/spondyloarthritis
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There are many conditions both autoimmune and non-autoimmune that can mimic PMR. Many of these conditions respond rapidly to prednisone but only the symptoms respond. Depending on the condition, prednisone might not be the best treatment. See Table 1 in the link below.
https://www.ccjm.org/content/87/9/549