@yanks950
I tried Abilify 2mg and then increased to 5mg. I was also taking 150mg Wellbutrin/bupropion. I seemed slightly better at 2 mg Abilify but started to get increased pain and difficulty walking (affected nervous system and muscles negatively) when it was increased to 5mg. I stopped after 2-3 weeks on the 5mg Abilify.

I was on duloxetine but maxed at 60mg. It worked at first but stopped after a couple years. What are your current symptoms? I am not as familiar with Buspar. I am currently taking 300 mg Wellbutrin/bupropion and just increased to 75mg Zoloft/sertraline. It is helping to treat my major depression. I also have chronic pain, neuropathy, spinal stenosis, osteoarthritis, etc. I’m 55 years old. Major depression can really knock you off your feet and keep you down/rob you of your quality of life so getting mental health support is critical.