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Prescribed Tymlos after Evenity

Osteoporosis & Bone Health | Last Active: Apr 23 8:22am | Replies (109)

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@gently

hollygs,
I'd go for another year of Tymlos. The TBS increase makes me suspect that the next year will yield greater bone mineral density. The right femoral neck is concerning. There is sense to be made of it from the type of bone that Evenity produces. And from the important canaliculation that Tymlos initiates.
Fatigue is one of the common side effects of Tymlos. I speculate the fatigue results because the dosage is too high-- probably not a good subject for conversation with your physician tomorrow. Most are so opposed to lowering the dose. Elevated calcium can also cause fatigue. Part of the mechanism of action for Tymlos is to increase serum calcium briefly. But in some people it can cause sustained calcium elevation.
I would ask for serum lab orders. P1NP and CTX, calcium, d and pth.
Thanks for posting the Evenity to Tymlos results. Very helpful.
Post us how your appointment goes.

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Replies to "hollygs, I'd go for another year of Tymlos. The TBS increase makes me suspect that the..."

@gently Thank you so much for your reply, I really appreciate it. My current labs are all in the normal range, and my doctor has told me she doesn't do bone markers as they're "not reliable". I'll discuss that with her again. There's no way of knowing how much Tymlos is contributing to my fatigue, but I will be off it for a month and that will be enough to gain clarity. It's quite likely that my doctor will stick to wanting to follow up with Prolia, and then I'll be up a creek without a paddle.