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DiscussionTips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)
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Replies to "Thank you, its so nice to know that this is normal to feel like this. (I..."
@elaine0
No you shouldn’t face this the next month because it will be a prolonged process. People are usually in a hurry to get off it and end up suffering the consequences. Some patients who have taken this medication 10, 20 or 30 years believe 1, 2 or 3 years is too long to wait to get off and usually pay the price of withdrawal symptoms. If you decrease too quickly then you may very well face similar issues the next month if not earlier depending on your taper rate and length of time between taper dosages.
Most doctors seem to have checked out of hotel reality when it comes to discontinuing this medication successfully. My suggestion would be to lower your dose by no more than 10% per current dose (3.75mg to 33.75mg then 3-4 weeks later decrease 10% again 3.375mg to 30.375mg) and use a compounding pharmacy. Getting your medication from this type pharmacy will take out any guesswork and assure you of getting exact dosages from start to finish. You’d never be able to get exact percentages or dosages by cutting or decreasing beads. If affordable compounding is the only way to go. Find a non-sterile compounding pharmacy. I’d also suggest lowering your dose below 10% as you get closer to zero to increase the probability of not having any symptoms. SLOWLY is the only way for most people to defeat this monster. Just use common sense and patience. I suppose it just depends on the level of discomfort your willing to tolerate. Personally I will do whatever it takes to avoid withdrawal and have successfully done so.
However you choose to proceed I wish you luck and hopefully an uneventful taper. Withdrawal free taper is possible but it’s not quick.
Good luck,
Jake
@elaine0
Your doctor is woefully unknowledgeable about getting someone off Effexor. Just advising you to “drink more water” is poor patient care, if not outright patient neglect. Your first doctor wasn’t much better (ill-informed and sexist)—mood numbness, lowered libido, weight gain ARE all reported Effexor side effects.
Withdrawal symptoms can get much worse when reducing at lower levels, especially if you make large reductions—going from 37.5 to 0 is a BIG drop. Getting impatient now isn't a good idea—as you are experiencing, it can be VERY unpleasant, sometimes dangerous (your blood pressure can drop dramatically, etc.) and worse, rushing the tapering process sets you back.
“If someone discontinues Effexor after daily long-term use, the brain continues expecting Effexor to be delivered …. neurotransmitter activity throughout the brain becomes chaotic as a backlash-type reaction to not delivering the drug that it had adapted itself to. It is the chaotic neurotransmission throughout the brain … that is likely responsible for Effexor withdrawal symptoms. Until the brain manages to re-learn how to function without Effexor’s presence, withdrawal symptoms will probably persist.”
—https://www.4mind4life.com/effexor-withdrawal-symptoms
Help your doctor learn about this issue—print out the articles I cite here for your doctor to read. You can ask your doctor about a "Prozac bridge" (softens the blow when withdrawing from a short half-life drug like Effexor)—essentially you take 10–20mg Prozac (fluoxetine) for a short period (weeks, a month) until your WD symptoms resolve, then taper off the Prozac over 2–3 weeks.
Why taper?
Besides minimizing withdrawal effects, tapering off an antidepressant decreases the risk that depression will recur. A Harvard Medical School study of nearly 400 patients were followed for a year+ after they stopped taking antidepressants prescribed for mood and anxiety disorders. Participants who discontinued rapidly (over 1–7 days) were more likely to relapse within a few months than those who reduced the dose gradually.
—https://www.health.harvard.edu/diseases-and-conditions/going-off-antidepressants
NOTE—You say you weren’t ever depressed. Be aware that quitting Effexor (and other antidepressants) can cause the very issues they were designed to treat as a backlash effect; your brain has to reset itself and learn how to act without the drug influencing it. Effexor makes profound changes to how our brains balance the neurotransmitters needed to function. When you stop, or significantly lower your Effexor, the brain has to wake up and start working by itself. The time this takes varies enormously.
How to taper—
Reduce your dose in increments (only 5–10%, or even less if you get withdrawal symptoms) and allow 2–6 weeks between dose reductions; if WD symptoms occur, go back to the dose where you didn’t have symptoms, stay there for some weeks, then try tapering again. I was on 25mg tablets–they were tiny, but easy enough to chip off slivers at the beginning and the end of my taper and cut into halves and quarters in the middle. Other folks count the beads in their capsules and guesstimate how many to remove at each taper. You can look for a compounding pharmacy to make specific tapered doses (may not be covered by your insurance and costs $s).