Within a day of my first Evenity shot, I was exhausted beyond belief. The entire month I was just barely able to do my chores (avid horse owner/rider). I was so fit and active that the change surprised me. I told the Osteo that I felt like I had a major infection and asked to change drugs. He urged me to try once more, which unfortunately I did. The second shot hit me hard again. I woke up one morning coughing so hard that I could not catch my breath. I'm very stoic, so I just trudged on. Within a few weeks, I had what I thought was a bronchiectasis flare up. I had stable bronchiectasis from 2006 pneumonia - with no flares until 2024 Evenity shot. I could not breath; my FEV was very low and my heart rate very high. My PCP prescribed antibiotic and pred. I did not relate it to the Evenity at that time. By the time I next saw my Osteo, I had located several articles about the effect of Sclerostin on the lungs, as well as ILD resulting from monoclonial antibody drugs. My Osteo sent me to get a lung function test - surprisingly low. Recent bronchoscope showed severe edema, plus infection. I don't know if it will be permanent. Of course, none of this can be proven to be caused by Evenity. Especially since the time to get these pulmonology appointments far exceeds the ability to link 'cause and effect'. But, as a retired pharmaceutical professional, I can see potential relationship given the literature (18 year symptom free until immediately after Evenity). I did make several reports along the way in the FDA database to document the symptoms. Effect to lung is not mentioned on the label. The articles below mention that time to onset of problems is not immediate - an important point.