Yes, it’s the way it interacts with the neurotransmitters in your brain. That’s one of the reasons I’m afraid to go back on. I’m afraid it won’t work! But moreso, I’m determined to stick it out as long as possible without Effexor. It’s been since February first after about 20 years on. I had two solid days of depression not lifting, but I’m also determined NOT to make any big decisions while depressed. So, I wait for the sun to shine and perhaps during a jog and then ask myself that question. I also gravitate to people who encourage me to stay off. It’s ultimately your decision, and, with all the supplements and even Eastern medicine remedies, perhaps try something different to get you through.

I honestly don’t know how I feel about it. Effexor worked for me, but on a personal note, it put my libido in the toilet. Still waiting for things to come back, but I have hope :).

Oh I wish I could turn back the clock.