← Return to Oxaliplatin is no walk in the park, advice for CAPOX regimen?

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@colleenyoung

@duane4cancer, it's not uncommon for an oncologist to recommend reducing the dose of a drug in a regimen or to eliminate it if the the side effects are limiting quality of life. My dad also stopped the oxiplatin in his regimen due to increasing neuropathy and to try and avoid it being permanent. He also had type 2 diabetes, so that increased his risk of neuropathy.

Duane, how long has it been since you stopped oxiplatin? Are you currently on any treatment?

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Replies to "@duane4cancer, it's not uncommon for an oncologist to recommend reducing the dose of a drug in..."

I stopped the Oxiplatin around the end of October. Then continued with four cycles of Capecitabine (2,000 twice a day/two weeks on and one week off). Finished around the 15th of January and had my CT Scans on Jan. 31st expecting to be cancer free. After discovering it had actually spread to my liver and peritoneum, the did a liver biopsy on Feb. 25th. (can't believe it took so long to get in). So that was sent in for genetic testing and my oncologist wanted me to start on Folfiri right away. But the biopsy scans showed no changes since the scans on Jan. 31st. So I decided to hold off on treatment until March 20, when we will start the Folfiri, and whatever immotherapy he has decided upon. I have Metastatic Mucinous Adenocarcinoma. I'm not convinced that Folfiri will work for that. But he did his fellowship right there at Mayo and is a smart guy, so giving him one more chance. The goal is the shrink the tumors in those areas, with possible HIPEC surgery later on. I would come to Mayo if we get to that point because of how specialized that is. Or maybe even the possibility of PIPAC, which seems to show more promise in cancer treatment. He's not an optimistic guy, and everything seems pretty textbook right now. But we'll see what happens next.