Endometroid Carcinoma with microglandular patter insight

Posted by acorvettemom @acorvettemom, 5 days ago

Just found out yesterday I have endometrioid carcinoma with microglandular patter. My doctor gave me zero info other than they found cancer cells and I feel like I'm grasping at straws. Can anyone give me any insight based off the following? I'm only trying to understand my DNC results and WILL NOT take your reply as medical advice. Scary stuff and have to wait a month before I can see an Oncologist and just trying to understand better.
***Multiple red-brown tissue fragments admixed with mucoid material, 2x2x0.2 cm in aggregate. Specimen is filtered and entirely submitted in A1. Microscopic examinations shows numerous fragments of crowded glands w/nuclear atypia abundant eosinophilic cytoplasm and areas of squamous metaplasia. There's abundant neutrophilic infiltration. Focal areas of residual endometrial mucosa are present. Immunohistochemical stains were performed for further chacterization. P53 shows wild type stainin, Ki-67 shows mild to moderately increased proliferative activity & findings are consistent w/endometrioid carcinoma with a microglandular patter. Thank you and any insight is helpful 🙂

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@acorvettemom Welcome to Mayo Clinic Connect. We aren't medical professionals here and cannot provide medical advice or provide a comprehensive interpretation of your pathology report. I do appreciate that you posted it here as it helps me to figure out what you have received. We offer support to one another and share our own experiences so I hope I can be helpful to you.

Here is something to read that will help explain what endometrial cancer is and different kinds of endometrial cancer.

American Cancer Society What is Endometrial Cancer:

-- https://www.cancer.org/cancer/types/endometrial-cancer/about/what-is-endometrial-cancer.html

It's no wonder you are in shock with these results. Have you talked with the medical provider (gynecologist?) who performed the D&C? A month before you see the oncologist is just too long to sit on this diagnosis. I'm going to recommend that you call the oncology office and ask for an earlier appointment or to be put on their wait list should they have a cancellation. You could also contact the medical provider who made the referral (your gynecologist?) and ask them to try to help push your appointment forward.

I will offer my experience with receiving pathology results after a D&C that too were utterly shocking to me. My gynecologist called me with the results (endometroid adenocarcinoma) and so I did not see the pathology result before he did. My gynecological then made room in his schedule to see me in person that very afternoon. After talking with him I took a wrong turn on my way home and got myself utterly turned around. I recognized where I was but it was a place I hadn't driven before. It took me a few moments to turn myself back to the roads where I was supposed to be. Anyway, I meet with my gynecologist again for the scheduled follow-up appointment a few days later and discussed the results and what I wanted to do. In my case there were no oncologists in my local area who specialized in gynecological cancers so my gynecologist offered a referral for me to either the University of Michigan or Mayo Clinic. I chose Mayo Clinic where I was already a patient. Within a day of the referral Mayo Clinic called me and I was scheduled that very same week to see a GYN-Oncologist. So, in my situation I did not have that long wait that you wrote - a month is way too long!

My husband is a pathologist (retired) and when I share with him the delays that some of us have faced here on Mayo Clinic Connect he is amazed--and angry. In the case of newly diagnosed cancer or suspected cancer he says that these long waits are just awful for two reasons. 1) if it is an aggressive cancer then it needs to be addressed quickly; and 2) it is simply too stressful for the patient.

So, with all this information would you like to call oncology and try to get in sooner?

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I appreciate your response. I have my D&C "follow up" appt w/my Gyno tomorrow and I'm now able to see the Oncologist on 3/18 (yay!) It's super frustrating being told I have this but literally no info about it. I tried getting my hysterectomy scheduled but wasn't able to until the Oncologist determines the course of action. I will keep being my own advocate & keep pushing for speed in getting this taken care of. thank you!

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@acorvettemom

I appreciate your response. I have my D&C "follow up" appt w/my Gyno tomorrow and I'm now able to see the Oncologist on 3/18 (yay!) It's super frustrating being told I have this but literally no info about it. I tried getting my hysterectomy scheduled but wasn't able to until the Oncologist determines the course of action. I will keep being my own advocate & keep pushing for speed in getting this taken care of. thank you!

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@acorvettemom This is very good news. Yes (I'm pumping my fist) and saying "way to be your own advocate". I'm so glad to hear that your appointment was moved to 3/18. I do hope that your oncologist will spend the time with you to explain your pathology results and discuss treatment plans. After your appointment with your gynecologist tomorrow and finding out what information is given to you at that time I'd recommend that you make yourself a list of questions/concerns for the oncologist.

Will you please let me know what happens with your appointment with your gynecologist tomorrow?

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Hello!!! Spent some really good time w/my OBG at today's follow up. Said everything looks and feels good. She said since she only did the DNC which involved only the lining, she was not able to tell me anything as far as my ovaries or anything else is concerned because she did not take any samples from those other areas. However looking at the ultrasound of the ovaries, she said they looked "dull" which is good. She mentioned the Oncology OB will be able to grade this usually once the hysterectomy is completed & explained the Oncology OB will read thru all my charts, files, slides and history & a panel of doctors will review everything together & then they'll determine what scans or anything I would need (if anything) before the hysterectomy. My doctor did say that the Oncology OB will try to get me in as soon as they can & they will not wait on getting the surgery scheduled. I did confirm w/the Oncology department they have recv'd my files & they're waiting to be read. (THANK YOU for replying & talking me thru this (even for a short time). It really makes good knowing there are a lot of caring people out there!!!

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