Starting Orgovyx - how long for side effects to occur?

Posted by daveinflorida @daveinflorida, Feb 17 11:02am

I've been taking Orgovyx for about 3 weeks and so far have zero side effects: no hot flashes, no fatigue or tiredness, no weight gain, no ED, nothing. I'm not complaining, but I'm on pins and needles waiting for stuff to start.

For background, I am in good shape and very active, I've been running for years and run 4-5 days a week, 30 - 35 miles, and also resistance train 2-3 days/week. I have no idea if that's what's doing it, but I'd be doing it anyway.

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toolbelt | @toolbelt | Feb 19 10:17am

In reply to @daveinflorida "Good to know. Today is day 21 for me." + (show)

Keep up the exercise. I was doing cardio at the gym 5 days a week, lifting 3 days a week, and walking 18 holes of golf twice a week. I had purposely lost 7 pounds prior to starting O and only gained 2 of that back.

johnny8924 | @johnny8924 | Feb 19 10:28am

Been on Orgovyx for 6 months. No apparent side effects except for occasional fatigue. I've been exercising and weight training 7 days a week without difficulties. Blood work in a few months will indicate if my blood lipid profile, CBC, A1C, etc are still normal.

rnpalarino1 | @rnpalarino1 | Feb 20 6:55am

I had my prostate removed almost three years ago. PSA began rising after about two years. I have been on Orgovyx since April 2024, with very few side effects other than my golf drives don't go as far. My oncologist is recommending I take a break from the drug while on a cruise and then a golf trip to Scotland restarting it again in about 6 months. He is "almost" certain my PSA numbers will again begin to rise again from < .01 after I stop taking Orgovyx. He is such a pessimist, but I know he is probably correct.
Thoughts???

johnny8924 | @johnny8924 | Feb 20 7:46am

In reply to @rnpalarino1 "I had my prostate removed almost three years ago. PSA began rising after about two years...." + (show)

You must be one strong human being, having your prostate removed 3 years ago, very few side effects from Orgovyx, and mastering that dastardly game of golf! A PSA reading of less than .01 is virtually undetectable for the presence of PSA. I would probably take a break from Orgovyx and have another PSA blood test within 6 months. I've been quite adept during my life playing baseball, basketball, football, tennis, and racquetball. Golf was harder than Stochastic Mathematics or Topology college mathematics classes.

heavyphil | @heavyphil | Feb 21 6:46am

In reply to @rnpalarino1 "I had my prostate removed almost three years ago. PSA began rising after about two years...." + (show)

You don’t mention salvage radiation as part of your treatment. Any reason you did not have it?
Phil

rnpalarino1 | @rnpalarino1 | Feb 21 7:44am

In reply to @heavyphil "You don’t mention salvage radiation as part of your treatment. Any reason you did not have..." + (show)

Phil:
I had my colon removed and replaced what is referred to as a J-Pouch. Consequently doctors don't want to give me radiation because it could cause damage to the pouch.
Nick

heavyphil | @heavyphil | Feb 21 9:07am

In reply to @rnpalarino1 "Phil: I had my colon removed and replaced what is referred to as a J-Pouch. Consequently..." + (show)

Damn…I’ve heard that from another forum member as well…hang in there, bud.
Phil

restlessandwild | @restlessandwild | 3 days ago

My six months Orgovyx has ended 2 weeks ago. Still have strong hot flashes, some muscle joint. How long this will take? Ill exercise 3-4 times per week, skiing or icehockey. Those two will end in two months because of summer. There is not much sun to bath, so how I should get my testos back? Magnesium, sun, d-vitamin? Something else? Ill try to get my penis also working after six m adt and 33x Radiation. 2,5y ago had RAPL.

jeffMar | @jeffmarc | 3 days ago

In reply to @restlessandwild "My six months Orgovyx has ended 2 weeks ago. Still have strong hot flashes, some muscle..." + (show)

It can depend On your age. It shouldn’t take more than a few months to get a lot of your testosterone back. You could get a blood test and see where your testosterone level is.

You can always get testosterone injections, but better to let it or return normally.

heavyphil | @heavyphil | 2 days ago

In reply to @restlessandwild "My six months Orgovyx has ended 2 weeks ago. Still have strong hot flashes, some muscle..." + (show)

I’m a month out from finishing ADT and the hot flashes are worse than while on Orgovyx….weird.
No supplement is going to bring your T back - short of T injections and you definitely don’t want those! I’m just gonna wait for it to happen.