I’m in a similar situation. My MRI came back PIRADS 3 and maybe pointing to a benign lesion. Radiologist said to do another MRI in 6 mos. Urologist would do a PSA in 3 months and a biopsy if my numbers increase or remain elevated. Not sure what to do. Wait for 2nd MRI or test and Biopsy. How is a PSE different from a PSA?