I have an almost identical situation. My CA 19 nine markers started going up gradually in early 2024. We started the discussions about chemo at that time. However, the medical profession and doctors always want to confirm. CA 19 nine markers with physical scans to confirm the existence of a tumor and location. I was scanned every three months with an CT scan, and as expected late last year, it confirmed that the pancreatic cancer had returned to the same spot. I’ve been on chemo now for two months and after a month, the CA 19 nine marker went from 1500 to just under 500. So you can see where I could’ve started chemo earlier in 24 if we had pushed it. Doctors are reluctant to do this without a physical scan to confirm the presence of pancreatic cancer. The plan now is for another month of chemo and then Photon radiation treatment followed by oral chemo. This recommended solution is specific to my case where they will go in with the Photon treatment through my back to avoid hitting other organs with the radiation. I had a Whipple procedure in 2018 and was good for five years. When it returned in 2023 the CA 19 nine markers started rising, followed by CT scan that eventually confirmed the tumor. At that time, the radiologist recommended stereotactic radiation, which is more focused than traditional radiation which can cover a wider area and hit the organs in the area. This worked for almost a year and my CA 19 nine markers went down below 34. So you can see the CA 19 nine markers for a perfect indicator of the return of the cancer, but the doctors are hesitant to go to the chemo early on until they can get the confirmation from a scan. I’m a believer of the accurate diagnosis of CA 19 nine marker for people with pancreatic cancer. God bless you. And I pray for your husband’s full recovery. 🙏🏼💜🌈