If you mean UCSF it's in San Francisco. (University of Calif., San Francisco) It's not downtown in the craziness of the city, but more of a residential area surrounds it. Stanford Neuro Center is about 40 minutes south of San Francisco. That would be another good option. Though UCSF is rated a bit higher in neurosurgery. If you fly into SFO (San Francisco Airport) taking an uber would be just about equal distance to either one. If you flew in through SJC (San Jose) it would be about the same 30 minute drive to Stanford. Second opinions are really important so I hope you find a neurosurgery department that is reputable and not too inconvenient.