@marushka9
Welcome to Mayo Connect. It must be frustrating to know there is a solution and then have to fight insurance company to continue. I hope you win your appeal with insurance company. If you do, definitely talk to your provider about the situation and if need to restart at lower dose.

We cannot provide medical advice on Mayo Connect only discuss our personal experience. I have never taken Wegovy, but @jc76 just posted about similar situation. He stopped for a while and then restarted at higher dosage and had terrible reaction. See his comment: https://connect.mayoclinic.org/comment/1251493/

Have you let your provider know about your situation and see if they have any advice on preventing the weight gain.

@marushka9
I want to make sure not giving you medical advice jjust what was told to me by my Mayo doctors that relate to your question and will pass what they told me.

My wife was having a lot of medical problems and I had just finished my 1.75 dosage. I was to start the 2.4 but I did not. I chose to wait a while and wound up waiting for over a month to start it.

This Monday took the 2.4 dose at night for first time. It was at least a month since finished 1.75. About 2 hours after taking I had nausea and headache. I had had NO side affects from lower dosages.

I could not sleep as the nausea and headache got worse. I got up at 4:30 a.m. on Tuesday and tried to take a medication pill I usually take when I get up with some food. I immediately felt extreme nausea and I vomited 3 times.

This went on again about 2 hours later. I portal messaged my Mayo doctor and was given a acute visit and here is what I learned.

You have to start with the lowest dosage to see what you side affects will be. You then go on to next dosage if needed and again see if side affects. This goes on until you reached the maximum dosage. You have to take your dosages per instruction and that is within 1-2 days of the last dosage.

I was told with a month of being off it my body eliminated the drug from my body and desensitized the drug in my body. So what I did was hit the body with the highest dose with no adaptation to medication required to have body adapt to medication. So NO if you have a break (per my doctors for me) that is extended and you want to start taking again you have to start at lowest dosage again and go through that process. If I want to start WEGOVY again I will have to start a lowest dosage and proceed each month to higher dose.

I was put on a clear fluid diet and told to drink full gator aide to get the sugar and electrolytes I need. They wanted to put me on a nausea pill but I have a heart condition and that medical affects my electrical issues. I am extremely afraid to eat anything of substance.

On Tuesday when I came home from my medical appointment it was less than 10 minutes and vomited again over and over. I was told each day after dosage my nausea and headache would decline and they are right. This is Thursday still have a slight headache. My stomach is still nauseated, bloated, constant burping but (knock on wood) have not vomited since Tuesday.

I wanted to pass on what was told to me reference if our insurance okays it can you start at 2.4 dosage again? You are at the same time frame I was having been off WEGOVY for about 5 weeks.

Maybe your case is different but wanted to pass on what I was protocol for prescibing the medicaions with any extended delay between dosage would have to start over. I am in misery and being on a clear liquid diet is horrible but at least I have not vomited.