@merpreb This is day 3 of cutting my 150mg Effexor dosage back by 25% at my doctor's instructions. I would have bet $$ that I would have withdrawal symptoms because the side effects are so awful if I accidentally skip a dose, but skipping a dose is 100% reduction and so far no problems at all at this initial reduction. I feel geat, no brain zaps at night which always clues me in that I forgot to take it in the morning. It really comes down to how each person reacts to weaning. My reason for starting on Effexor was anxiety so I will be on the lookout for any reemergence; it so often shows up in my dreams first which is kind of interesting. I hope I won't have any problems when I have hip replacement surgery later this year but will make sure all the docs know where I am with the Effexor. You were one of the lucky ones as far as the side effects. None of us knows how we will react until we actually start the process. Appreciate all the info here for sure. Blessings to all.