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Recent PSMA PET does not detect cancer, what’s next?

Prostate Cancer | Last Active: Apr 24 12:49pm | Replies (37)

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Thank you for the information. My Gleason score was 4+3,,PSA pre RP was 7.5.
That’s what I’m kinda confused about, the rib spots may be nothing. I have no doubt that I have BCR and last PCMA-PET showed nothing new. Your situation with the femur spot makes a lot sense. Do you wait for PSA to keep going up to have a higher chance to see something on the scan, go on ADT and blast away with radiation? SHEESH!

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Replies to "Thank you for the information. My Gleason score was 4+3,,PSA pre RP was 7.5. That’s what..."

Yes, I based my decision on a PSA value that rose very, very slowly for about 4 yrs; and then rose faster with each blood draw every 3 mos. So the rise AND velocity told me that I had BCR.
Other members may have some info on this, but I think the type of tracer used in the scan shows up differently - or not at all - in certain types of PCa. That is the confusing part: having bones light up, but not soft tissue and that PSA bounce definitely indicates prostate origin. And if your next PSA shows a DROP, then you have even more evidence that the bone lesions were PCa.
But other men have had PSMA’s that just showed bone mets and nothing else as well so these scans are clearly (yuk) not the bottom line - It’s steady PSA rise and velocity. Perhaps a PSE test might help here - not that I believe it is definitive either - but it may give you more info that you really need.