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Prolia for Osteoporosis

Osteoporosis & Bone Health | Last Active: 2 hours ago | Replies (40)

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@ladyjds

I appreciate you taking the time to respond. So much information out there on social media difficult to decide what is correct.
Aches and pains and since November knee pain. After PT - pain continued results from MRI - torn meniscus on right knee. Surgery scheduled. Left knee also problematic but not as painful as right. Due for my 6th injection in April but decide to delay to May to give me time to recoup from surgery. After reading about others side effects mine have not been as drastic but the longer I stay on Prolia and my age this drug will take a toll on my body. Thank you for your time and support.

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Replies to "I appreciate you taking the time to respond. So much information out there on social media..."

How long you can safely delay a scheduled Prolia injection should be thoroughly researched. Perhaps you could consult with your doctor or try to find some authoritative info. Best to look for research papers than rely on anything people say on social media sites.

I recall researching this issue when I was on Prolia and what I remember is that a delay of one month might not be a good idea, especially if you have been on it for a while. I no long have that research as I stopped Prolia almost 2 years ago. But the information is out there.

Good luck.

"We found that delayed denosumab dosing, even short-term delay of 30 to 90 days, was significantly associated with an increased risk of incident fracture for all clinical fractures as well as vertebral fractures in the following 6-month period. In addition, as the dosing time was further delayed, the risk increased even more. There did not appear to be a substantial influence on fracture risk if the administration was delayed within 30 days of the previous injection. This study further confirms that the timing of subsequent injection is critical in the management of osteoporosis for those treated with denosumab."
https://www.e-enm.org/journal/view.php?number=2552#:~:text=Increased%20risks%20of%20fractures%20with,consistently%20observed%20for%20vertebral%20fractures.&text=Delayed%20denosumab%20dosing%2C%20even%20by,be%20emphasized%20when%20starting%20denosumab.