Thanks for clarifying.

PI-RADS 3 means the findings are neither clearly benign nor obviously malignant (equivocal).

Also, the lack of focal lesions and a well-defined capsule makes a diffuse malignancy less likely. Prostatitis (inflammation) or other non-cancerous conditions could also explain these findings. I’d recommend watching Dr. Mark Emberton’s presentation on “MRI-invisible lesions and low risk prostate cancer”…it was incredibly useful for me.

Your prostate volume (95 mL) is significantly enlarged (normal is ~20–30 mL), which could be due to benign prostatic hyperplasia (BPH). Larger prostates can elevate PSA due to increased tissue volume rather than cancer.

One thing I learned when studying the effects of exercise on slowing PCa progression is that weight reduction can also cause PSA to decrease. Therefore, you might want to have your PSA retested, if you have not already done so since losing 20 lbs.

Finally, I found that by inputting all my test data (including my MRI report), as provided in its original form, into Grok3, I was able to get a layman’s explanation of its meaning which was quite useful in explaining things that were confusing to me. It’s not a substitute for your doctor, but it can help clarify obtuse medical language and seemingly conflicting test results and statements.

All the best,

Alan