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Anyone get the Decipher test: RNA Tumor RNA Expression Analysis?
Prostate Cancer | Last Active: Mar 15 3:03pm | Replies (5)Comment receiving replies
My interest was the lower right section pertaining to "neuroendocrine-like." Anyone have experience in that area?
Replies to "My interest was the lower right section pertaining to "neuroendocrine-like." Anyone have experience in that area?"
@rabaldwinjr, fellow member @billyh and @rnb122,wrote about neuroendocrine involvement and may have more to add.
See these related discussions: https://connect.mayoclinic.org/group/prostate-cancer/?search=neuroendocrine&index=discussions
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No experience here but this is exactly the type of information Decipher will help with.
"In general, NEPC differ from conventional PCa histologically by presence of neuroendocrine cells which do not express generic PCa markers like AR, P501S, PSMA, PSAP and PSA but characteristically expresses neuroendocrine markers such as chromogranin A, synaptophysin, CD56, and NSE."
It might mean that your cancer has the potential to be more aggressive.
"The Decipher Genomic Resource Information Database (GRID) is a novel research tool that captures 1.4 million marker expressions per patihttps://decipherbio.com/decipher-prostate/physicians/decipher-grid/ent and may facilitate precision-guided, individualized care to patients with prostate cancer."
https://decipherbio.com/decipher-prostate/physicians/decipher-grid/ 18 minutes into the video there is a sample grid--the portion most patients never see.
"Neuroindocrine [LIKE]" means that it it has similar tissue, but still may not be a fully neuroendocrine cancer.