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52 years old BRCA 2 positive with a gleason 6 score
Prostate Cancer | Last Active: Mar 6 1:52pm | Replies (27)Comment receiving replies
You're being treated/cared for at Sunnybrook. The "father of active surveillance", Dr. Klotz practices and does research at Sunnybrook. You have an interesting situation. Gleason 6, if that is what you truly have, does not metastasize. It is as close to not having prostate cancer as one can get.........hence Active Surveillance. It can evolve into something more serious......hence keeping an eye on it is critically important. You might look into getting a consult with Dr. Klotz or someone of high caliber in his practice. Here is a very interesting presentation by Dr. Klotz which may be of value to you. Dr. Klotz's presentation starts at about 1:34:22 in the following video. https://www.youtube.com/watch?v=CLHYu1SqsUw&t=5662s
Replies to "You're being treated/cared for at Sunnybrook. The "father of active surveillance", Dr. Klotz practices and does..."
Thanks so much for this info. I put in a request to see if I can speak to Dr. Klotz. In this video he clearly makes mention of BRCA and how he personally feels AS is not the preferred route in lieu of treatment for this mutation. I'm hoping for more direct clarity as I must assume he's in talks with the head Dr that's involved in this MRI and Biopsy trial.
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Those are good points; still, in addition to the Gleason score, don't forget that the OP's care team will also be factoring in that he has the BRCA2 genetic mutation.
Still, if an oncologist at Sunnybrook recommends active surveillance, I'd probably go along with them. As I mentioned earlier, the mutation isn't ones destiny, just an extra consideration to juggle in the risk/benefit decision. It means the OP and care team have to be a little more vigilant and proactive.
The benefit of PSA monitoring is that you can see prostate-cancer changes happening quickly — even if the absolute value is hard to interpret, the direction it's moving (rising, falling, or staying steady) gives you and your care team an early warning that something might be changing, so you won't be navigating in the dark.
Again, best of luck!