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Switching from Lupron to Orgovyx.

Prostate Cancer | Last Active: Mar 10 11:10am | Replies (28)

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@round5

You are correct in my case. I qualified for Neubeqa As an add-on to Lupron and Docetaxel
which is the triplet therapy (and I also received Carboplatin). All this was followed by Pluvicto. I know Lupron is in the gonadotropin-releasing hormone (GnRH) analogue family of medications. It works by decreasing gonadotropins and therefore decreasing testosterone and estradiol and I think Orgovyx is too,it just won’t linger in the bloodstream like the injections do. Nubeqa is an Androgen receptor pathway inhibitor. It is my hope/prayer that I can regain a normal level of testosterone in my bloodstream for the other normal functions of my body and that the Nubeqa will still block the testosterone at the cancer receptor site. I hope that all makes sense.

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Replies to "You are correct in my case. I qualified for Neubeqa As an add-on to Lupron and..."

First I've heard of this one. I have a sit down with my oncologist 4/1 /2025. Sure like to do something rather than nasty Lupron. I quit my second session 2/18/2025 due to SE's First session quit 3 years ago again, horrible SE's. Now only Prednisone plus Abiraterone both have SE's How bad? hard to tell as Lupron is still lurking in my blood stream. Would be great to be able to quit both and go with Nubeqa only.

Many thanks,
SW