← Return to ADT for several months before Radical Prostatectomy

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ADT for several months before Radical Prostatectomy

Prostate Cancer | Last Active: 1 hour ago | Replies (26)
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@krs03

Yes, understood. My surgeons don't suggest radiation for some time, I'm 14 weeks post RP. There is also the 'salvage' philosophy saying that no intervention is needed until there is a significant rise in PSA (0.5 or even >0.2). My counter argument is: I've never had a PSA above 10 and have had significant PC. So should I trust just this measure?
The adjuvant path is more aggressive in my view and has ADT along with SBRT for instance. When I have the oncologist on-board I'll express my concerns. Still there is a suggested healing time after surgery prior to any radiation.
Thanks Phil

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Replies to "Yes, understood. My surgeons don't suggest radiation for some time, I'm 14 weeks post RP. There..."
heavyphil | @heavyphil | 6 hours ago

I am a bit confused. You had a Lupron shot, but then say if your T rises you’ll want to go on Orgovyx. Don’t think you can do that - how will you ever measure your 3 month PSA’s accurately if you are on ADT?
So if you are anxious about a rise in T/PSA and you desire ADT, you almost have to have radiation sooner, way before the .2 level. If you don’t you “could” become castrate resistant (emphasis on could) the longer you stay on ADT without doing something definitive about the cancer. Radiation will damage cancer DNA and hopefully the cells will die. That’s the one-two punch you need.
It’s good that you are consulting with someone other than your surgeon. Surgeons will always tell you to wait as long as you can in the hope that their surgery will be successful. They never want to share the glory with a radiation oncologist who steps in and mops up what they missed. No judgment just the facts.

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