I took it for a year and was using a wheelchair at the airport and the pain was becoming unbearable. A nurse gave me the fyi that it was the Letrozole and I am so grateful. After 5 years off of it I have almost totally recovered. I am not sure that some of my pain is from aging and fms , but the worst effects of Letrozole was the contracting of my joints and fingers. My left hand still has some of those signs but it is not all the time. So I just what I want to tell you is yes I did recover. They gave me tamoxifen and I took it for a while but then refused it. I don’t regret it but of course my cancer has not returned. Good luck.