During my 2 years on ADT (lupron, abiraterone, prednisone) in conjunction with proton therapy for Gleason 9 localized PCa with EPE, my red cell count, hematocrit and hemoglobin lowered to a bit below the low normal before a more rapid decline (along with my white count which had previously been stabe) 6 months following the time the lupron should have been out of my system. I had had swelling in my legs due to edema which, for more than a year, had been atributed to the ADT. It worsened and joint pain developed. At the same time other blood work and physiological dysfunctions began to take place. During my time on ADT, I had been out of contact with my primary care doc, an internal medicine specialist. I had the mistaken belief that the oncologist would monitor and address side effects which resulted from treatment. I finally messaged my PCP for help. Long sorry short, she reviewed my case and in short order had me tested for a thyroid issue. The test came back positive for hyperthyroidism. Thirty days after begining meds for that, nearly all symptoms have resolved, including the swelling, joint pain and all blood counts. The lesson I took from this was to remain in close contact with my PCP while undergoing onclogy treatment as there are many other conditions which might cause, contribute or exacerbate symptoms which commonly result from ADT.

You two have really been dealt a tough hand. My hope is that you are able to connect with someone who is able to find the path to address your husband's cancer, symptoms and fractures. My heart goes out to the two of you. I hope you will continue to share the story.

Bill