No, they did not estimate how long I have had it. I’ve actually never heard of anybody getting that information…. But….. I had a biopsy about a year before the one that came up with Gleason 3+4, and there was nothing found. When they examined my prostate after surgery, it was 4+3, Something the biopsy never located. It could’ve been a year before If they had hit the right spots, it would’ve found something.

A few months ago, I saw a webinar where they really got into the reasons for not doing anything with someone who has a Gleason six. Unfortunately, it was never made available to view again. It was done through the Mayo Clinic on Dec 12,2024. I did Capture a number of screenshots during the webinar. I’ll look through them and maybe post Some of them in a future message.

Your PSA is very low and you have nothing showing in the MRI, Why did they do a biopsy? What made them suspicious that something was wrong besides the fact that you have BRCA2.

It is true that about 10% of prostate cancer patients do not produce PSA, So it stays low, even though the cancer is getting worse.

Im 52 also, had surgery last year. Initially, i was told i was a Gleason 6, and my PSA was 6.8. I got a second opinion (at Mayo, Phoenix), and was "upgraded" to a Gleason 7 (3+4). In my case, i was told surgery was needed due to the cancer pushing against the gland, risking it penetrating the barrier of the prostate . If your PSA is .5, and you're a Gleason 6, rest easy. As mentioned above, some doctors dont even consider a Gleason 6 to be cancer. If i were in your shoes, i'd watch the PSA to see if it starts climbing.