My feedback on using Linzess:
I have been on Linzess 290 since June 2024. It has worked wonderfully. For me it worked within hours. I am so glad to find a doctor that did something other than tell me to eat more vegetables and fiber....... which I kept getting told for decades. Sometimes I would just quit eating.
I started on 145 but discussing it with one of my siblings she informed me that they made 290 also. So I asked my doc for 290. If I was still working it would be a problem because I take it at about 0330 ..... by about 0700 I am processing and usually keep having for about 4 hours here and there. I am just so glad to not be constipated.
IF you have close relatives (like siblings) consider asking..... I had never heard of it and I could have just asked one of my siblings...... anyway, I do not have any side-effects as far as I can tell after 7+ months.