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PSA Nadir main deciding factor when one can start on Intermittent ADT?
Prostate Cancer | Last Active: Jan 11 9:26pm | Replies (31)Comment receiving replies
The length of time you stay on ADT (Orgovyx) is pretty dependent on your Gleason score.
If you were Gleason 8 then 18 months is recommended. If you are a Gleason nine or 10, then 24 months is recommended. Gleason 7 then 6 months.
You’ve been on Orgovyx Longer than someone with a Gleason seven would need to be on it. You can discuss this with your doctor. Some doctors let people stop ADT if they’ve been Undetectable for a long time and didn’t have other issues that could cause reoccurrence.
Did you have a decipher score? That could also be a factor in deciding how long you should take ADT.
Replies to "The length of time you stay on ADT (Orgovyx) is pretty dependent on your Gleason score...."
JEff,
Do you know of any cases someone with Gleason 9 or 10 and were on ADT for 24 to 36 months and still had cancer recurrence with metastasis within a year or two?
JeffMar, Are you a doctor? Just curious where you are coming from with these numbers. I am Gleason 9 Grade 5.
Thanks
@jeffmarc
If Gleason 7 unfavorable (4+3) and only got 20 fractions of 3 Gy’s each and decipher .88 How long should I stay on orgovyx.? Lymph nodes not radiated. No boost to tumor. Radiation started on day 11 of orgovyx no testosterone was 750 before radiation psa had gone from 9.4 to 11.9 diagnosed prostate cancer July 20. Radiation started Nov 10. Psa today .209 and testosterone < 2.5. I am I month post radiation and 2 mo post onset of orgovyx. I wanted boost to MR detectable tumor doctor refused also wanted whole pelvis radiated doctor denied. Now recommending only 6 month of adt. I think I need it longer as
Decipher.88 and radiation treatment borderline?
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I was Gleason 9(4+5) and decipher score 0.98
My Radiation oncologist (Amar Kishan) says 1 year, my oncologist at UCI says 18 months, but Dr Scholz of PCRI says, I should take a holiday from ADT, as I get very little benefit by continuing on ADT, sacrificing quality of life. Dr Scholz told me that I can stop when I was on ADT for only 9 months and PSA was 0.06. My oncologist at UCI says even if my PSA is ZERO, I should stay on ADT for 18 months, if I can tolerate it. He says cancer cells are not dead; they are just sleeping and can wake up when you stop ADT too early. Dr Scholz says, I go back on ADT if that happens.
I am getting an MRI on April 8th, per Dr Kishan's recommendation.
For now, I will stay on ADT. I will post it here my MRI results.