My husband was diagnosed with a Gleason grade 9 prostate cancer nodule ( that had NOT spread outside of the prostate) and was treated with 9 months Orgovyx and 28 days of targeted radiation. The Orgovyx caused severe joint swelling and pain (along with the usual hot flashes , erectile dysfunction and organ shrinkage) and severe drop in RBC count, hemoglobin , and abnormal liver enzymes. Our doc insisted he stay on Orgovyx but my husband lost the use of his legs at 9 months which we eventually learned was due to 2 severe bone fractures in his sacrum which will NOT heal. He now has a blood infection due to depressed immunity but the risk/benefit of this ADT treatment was never discussed with us. I do not think the Testosterone numbers really say anything about the recovery times after ADT. Any info after stopping Orgovyx ( we are now 7 months since stopping) but side effects like fracture , loss of libido and anemia seem permanent. Any info for this caregiver?