Connect
My 67year old dad had a PSA of 14 and it now reduced to 12 after 10d
Hi,
My 67-year-old father recently had a PSA test with an initial result of 14.62 ng/mL. His doctor suspected prostate cancer and recommended a TRUS-guided biopsy, which was performed. The biopsy results showed only benign prostatic tissue, with no evidence of malignancy.
As a follow-up, we repeated the PSA test after 10 days, and the result dropped to 12 ng/mL. However, despite this decrease, the doctor insists that the PSA has not reduced enough and is recommending another biopsy.
We don't know what to do now. We don't want to do another biopsy.
But his PSA is also pretty elevated. What do we do now?
We're not happy with this current doctor as he didn't look at the test results properly and didn't answer our questions promptly too.
Like
Helpful
HugInterested in more discussions like this? Go to the Prostate Cancer Support Group.
Connect
Seek another urologist, especially if you aren't happy with the current one.
A high PSA doesn't guarantee cancer, just as a low PSA doesn't guarantee no cancer. You can ask for a PSE test, instead, this should give a 94% accuracy if there is cancer - and it's only a blood test. PSE should generally be done before biopsies for this reason.
-
Like -
Helpful -
Hug
1 ReactionMy first biopsy came back Benign and my PSA was 6. I just had an additional biopsy and the PSE test and the biopsy both agreed that I have Prostate Cancer. You dad's next step should be a PSE , based on that, he might have to have a second biopsy. Biopsies aren't fun and I certainly didn't want a second one.
-
Like -
Helpful -
Hug
4 ReactionsHas your doctor talked about BPH at all? That can cause your PSA to rise and not be prostate cancer. The usual treatment is an antibiotic, but if you don’t sell any symptoms, then that won’t help.
A friend of mine had a PSA of over 50 went through multiple biopsies and never had prostate cancer. That PSE test mentioned Is probably your next best bet. Here’s some info about the PSE versus other tests
-
Like -
Helpful -
Hug
3 Reactions@manishpaulsimon
I agree with everyone’s recommendation to take the PSE test.
If you have any questions about this test, you and, or your doctor, can contact Steve Arrivo who is a senior VP at Biodynamics. He Is more than happy to answer any questions. His email address is: steven.arrivo@oxfordbiodynamics.com.
Part of their goal as a company is to help people decide whether they have prostate cancer both, before they have to do a biopsy but also, even after treatment, if a biological reoccurrence happens, it can be used to discover cancer has re-appeared.
I would also suggest as a layman, to go to a center of excellence via Telehealth to get another opinion. Mayo Clinic is an obvious choice, but there are several out there.
-
Like -
Helpful -
Hug
3 Reactions@manishpaulsimon
Sorry to be so lengthy in my response, but here is a response from a VP at Biodynamics to give you and your doctor some more clarity:
Here is the comment made by Joe Abdo, the VP of Clinical Diagnostics for Oxford Biodynamics further r clarifying the PSE test:
"Just to clarify, the EpiSwitch PSE test analyses immune cells in the blood that have been at interplay with prostate cancer (or not). Your PSA value only makes up a small portion of the results of the test. There are other very informative biomarkers assessing the presence or absence of PCa included in this test. So yes, EpiSwitch PSE can still be used with a very low PSA score, and can still detect prostate cancer without PSA shedding. Therefore, the test can be used before, after and during treatment - even after complete prostate resection. In your case, a 'low likelihood' result could potentially help you avoid things like PSMA scans if your PSA indeed rises over time. A 'high likelihood' result could be indicative of recurrence, irrespective of low PSA."
-
Like -
Helpful -
Hug
3 ReactionsBen. Once again you’ve come up with a gem! Having just finished radiation/ADT my PSA tests are really gonna have a BIG impact on my mental health and anxiety levels.
More than just if the number rises, but the interpretation by the oncologist as to whether more treatment is indicated. If it is, so be it - but you really need to KNOW that it’s necessary. Thanks again.
Phil