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Persistent Positive ANA, Now DFS70 – Does This Indicate Recovery?
Autoimmune Diseases | Last Active: 5 days ago | Replies (10)Comment receiving replies
I have had a speckled ANA positive
A speckled ANA pattern indicates the presence of antibodies that target specific proteins in the nucleus of cells. This pattern is often associated with autoimmune diseases such as:
Systemic lupus erythematosus (SLE), Sjögren's syndrome, Scleroderma, and Rheumatoid arthritis
Have you had the gland biopsy by an ENT and the test by the eye doctor for Sjogrens?
DFS70 antibodies are a subgroup of ANA that appear as a fine, dense speckled pattern under a microscope
They are found in 10% of healthy people, but only a small number of people with autoimmune rheumatic disease
They are a useful marker to help distinguish people with positive ANA who don't develop systemic autoimmune disease
Positive Ana still means your autoimmune system is messed up. Mines always high.
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My ANA is Abnormal. Not negative or positive. I’m not sure what that means.
After loads of blood work reviewed in detail by my Duke rheumatologist, neurologist, endocrinologist, ophthalmologist and ENT, they don’t think I have an autoimmune disorder, such as lupus, Sjogren’s, etc. I feel I need to trust their opinion. I have worked on my health anxiety with my therapist for over a year and he encouraged me to advocate for myself medically, then accept the diagnosis. So, I’m moving forward. Fortunately, I’m doing really well and except for a few issues, feel awesome.
Oh, BTW, my grandfather had RA, as do several first cousins and uncle. My aunt has lupus. Another cousin has type 1 diabetes like me. And another cousin has psoriatic arthritis. I was negative for RA, but do have psoriasis.
We are of eastern european descent.