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Prednisone dosage split

Polymyalgia Rheumatica (PMR) | Last Active: 5 hours ago | Replies (20)

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@michik

@janetilley did taking it that early in the morning, I am assuming without food, not upset your stomach eventually? I have developped so much abdominal discomfort, acid reflux and heart burn, even tough I am on an acid suppressant (PPI) and make sure I take my prednisone with food and a big glass of water.
I tried splitting my dose for a while when I was at 13 mg. I did 11mg with breakfast and 2mg with supper. But my acid reflux seemed to get much worst in the evening. So I am back to full dose in the morning.

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Replies to "@janetilley did taking it that early in the morning, I am assuming without food, not upset..."

Yes I always take prednisone with food- buried in a spoon of yogurt! It’s the only way for me. I kept it beside my bed. Taking it at breakfast was too late for me- too much pain getting out of bed. I’d rather get the pred working as I slept. It has never disturbed my sleep. Plus I’m up 2-3 times anyway for bathroom. Family trait. I’m at 3 now and ready to taper to 2.5 in two weeks. Evening dose now works best. I found it best to adjust habits as PMR evolved. What works at one stage, may not be best as disease progresses. I learned that tactic early on from this chat room. As I’ve learned so much. Good luck.