Yes, everyone is different. My rheumatologist started me at 10 mg, which seemed low and it took several weeks to eliminate the pain completely. I asked if I needed a higher dose, but he said to be patient. Sure enough, I eventually became pain free and shot on past that to superwoman. I went from feeling 100 years old to feeling 30 years old (I was 68). He then had me taper at my own pace. With the help of the online community, I decided to do the dead slow taper and had no problems until I hit 1.5 mg. Then I had bilateral back pain for a few days. Then it went away. At .5 mg I had right knee pain for a few days. Then that went away. I never increased my dose or took any other pain meds. I have been prednisone free now for 7 weeks with no issues except morning stiffness. I am 70 and feel it, but nothing like PMR. I hope my experience is useful to someone. Dr. Bravo did me right!