PSA never reaching undetectable

mlandry, call the frazzled doctor and get an order for a PSE.
https://www.94percent.com/?gad_source=1&gclid=Cj0KCQiAq-u9BhCjARIsANLj-s1u1mukwXJ7ctds7JveHHAv0YNYUMlZBDwiNcXfRavC_NsQYKI6LToaAodOEALw_wcB

After radiation, the PSA does not always drop to Undetectable. Some people have taken three years to reach the low point. It could be your low point and target is around .27. The fact that it is not rising multiple times in a row is the key. If you get three rises in a row, it is time to think about doing something. So the point is, your PSA can bounce around, people do get paranoid when that happens, but it really is not abnormal.

When I was on a zytiga for 2 1/2 years, my PSA went as high as .7 to as low as undetectable, but it always bounced around. Now I’m on Darolutamide, and I’ve been undetectable for 15 months, Different drug different results. The bounces didn’t matter.

@mlandry
From your post I assume you only had radiation with hormone treatment not prostate removal.
Who told you your PSA would go to undetectable after treatments? I would really asked again who told you that.

An undectable PSA is seen in patients with prosate removal not prostate radiation. I had radiation and the goal of my UFHPTI was a PSA of below 1 (one). I am at that now at .22

I was told by UFHPTI and Mayo that I would have bumps up and down on my PSA. This is normal when you still have a prostate. Having PSA levels with a prostate is completely normal and expected. What you want to worry about is a PSA that keeps rising and rising not just a bump up and down here and there. A .3 is very good not bad. It is below one and you did have a bump up just like I did but then a bump down. I am at .22 now but previous was .51 that was a bump from .41 the previous PSA test. I was told the bump was completely normal and to expect them.

I am not sure why you think that a .3 is even something to worry about still having your prostate. I would really dig into asking questions of your urologits and R/O about PSA levels and what is good and bad. Your PSA going to undetecable when still having a prostate is unrealistic nor the expectation of any urologist or R/O ever saying will happen with still having a prostate. Guess it could be really low if still on hormone treatments but with a prostate you are going to have PSA numbers.

Maybe I didn't explain it well enough- I realize *after* treatment the PSA will be higher, my concern is that while still on ADT, the PSA never got below .1, which my understanding is that it should, if things are going the way they are supposed to. Here's what AI says when I looked it up after watching the video: AI Overview

If a patient's PSA level is not undetectable while on androgen deprivation therapy (ADT), it means that the prostate cancer is still detectable and not completely suppressed by the treatment, potentially indicating a less favorable prognosis and the need for further evaluation or treatment adjustments; a detectable PSA level on ADT could suggest the cancer is progressing or may not be fully responding to the therapy.
Key points about a non-undetectable PSA on ADT:
Potential for progression:
A detectable PSA level, even if low, can signify that the cancer is still growing and may eventually progress to a more advanced stage.
Monitoring required:
If PSA is not undetectable, close monitoring with regular PSA tests is crucial to track any changes and assess treatment effectiveness.
Further treatment options:
Depending on the situation, additional treatment options like radiation therapy, chemotherapy, or newer hormonal therapies may be considered for patients with a detectable PSA on ADT.