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If I already have a gleason score of 3+4 through biopsy, is there any advantage to getting a PSE? I never had that blood test.
Also, I'm struggling with deciding what treatment to go forward with, including monitoring. I've had 36 biopsy samples, of those three have a Gleason score of 3+3 and one a Gleason score of 3+4. The 3+4 represented 5-10% of the sample. That is the extent of the cancer found. I've been through an MRI that showed two lesions RAD-4, but after guided biopsy didn't show any cancer. In my mind, with only one spot identified, nothing outside the prostate, why risk the side effects of surgery or radiation. I am 66 with a PSA of 8.3. Any thoughts?
Replies to "If I already have a gleason score of 3+4 through biopsy, is there any advantage to..."
My second MRI, 4 years after the first, showed no signs of cancer, but my biopsy after the MRI showed two cores of cancer, one at 3+4. I opted for surgery. The post op pathology report showed that my cancer was actually 4+5. And they also did a Decipher test which showed I was high risk. My point is: my tests were very inconsistent. My pathology report showed a higher grade of cancer. I was glad I got the RP. BTW, 15 months since my surgery, my 4 PSA tests have been < 0.01. Hoping and praying for more of the same in my upcoming appt. Ask lots of questions. Best of luck in whatever path you choose! 🙏🤞
I did Tulsa Pro for Gleason 7(4+3). My PSA was 8.6. It was an easy process as I had only 30% of my 45cc prostate ablated. I didn’t feel like I was risking much of anything as the side effects are usually minimal, and all other treatment options are still on the table if the cancer returns. Literally no pain and I was back walking my normal 4 miles per day the next morning. At 6 months there is no sign of cancer. Medicare and my supplement paid it all.
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I agree with @survivor5280, it would be real interesting to see a decipher test result. The PSE test would not make a lot of sense since you already know you have cancer and have already had a biopsy. It’s just a matter of how much there is and how quickly it grows Noe.
If you have one 3+4 you are a Gleason seven the 3+3’s are not relevant anymore.
PI-RADS 4 is pretty much known to be cancerous. It would be good to know how big they are and where they are. Are any near margins of the prostate.
Yes, you could go on active surveillance. You don’t mention your PSA, which could be useful. What you’re looking for is PSA doubling time. The shorter it is the more likely you have to get off of active surveillance and do something.